https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18018 Wed 11 Apr 2018 15:54:12 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28988 a]pyrazine derivatives has been developed as inhibitors of the VirB11 ATPase HP0525, a key component of the bacterial type IV secretion system. A flexible synthetic route to both 2- and 3-aryl substituted regioisomers has been developed. The resulting series of imidazo[1,2-a]pyrazines has been used to probe the structure-activity relationships of these inhibitors, which show potential as antibacterial agents.]]> Sat 24 Mar 2018 07:29:24 AEDT ]]>